Qhov txawv ntawm Chitosan thiab Chitooligosaccharide.

Chitin tau tshawb pom los ntawm Fabkis tus kws tshawb fawb Braqueno hauv xyoo 1811 thiab muab rho tawm los ntawm crustacean plhaub los ntawm Ogier hauv xyoo 1823 thiab hu ua CHITIN. Cov tsos thiab cov yam ntxwv: lub teeb beige rau dawb.

Chitin yog cov khoom siv tau zoo thiab thawj "cov khoom noj muaj txiaj ntsig" tau pom zoo hauv Nyij Pooj. Txawm li cas los xij, chitin yog insoluble hauv dej, alkali, cov kua qaub thiab cov kuab tshuaj organic, thiab tsuas yog soluble hauv qee cov kua qaub. Nws yog ib nrab decomposed los ntawm kev ua ntawm chitinase thiab lysozyme nyob rau hauv tib neeg txoj hnyuv. Yog li, nws qhov nqus tau qis heev, qhov ntau npaum li cas, thiab cov tshuaj tiv thaiv rau kev noj yog siab li ntau tshaj 70%. Kev kho tshuaj ntawm chitin, tshem tawm cov pab pawg acetyl, dhau los ua chitosan.

Lub npe Askiv: chitosan

Lub npe tshuaj: polyglucosamine (1-4) -2-amino-BD glucose

Molecular formula thiab molecular hnyav: (C8H13NO5)n

Properties: dawb, tsw, tasteless, insoluble nyob rau hauv dej, soluble nyob rau hauv acidic tov

Chitosan, tshuaj hu ua polyglucosamine (1-4)-2-amino-BD qabzib, yog tau los ntawm deacetylation ntawm chitin. Feem ntau hais lus, chitosan tau txais thaum ntau dua 55% ntawm pawg N-acetyl raug tshem tawm. Chitosan twb soluble nyob rau hauv dilute acid, uas yog ib kauj ruam tom ntej ntawm chitin. Txawm li cas los xij, ob qho tib si chitin thiab chitosan yog cov molecules loj uas muaj qhov hnyav molecular xws li ntau pua txhiab mus rau lab, thiab tsis soluble hauv dej. Chitosan yog tau los ntawm deacetylation ntawm chitin, thiab tom qab ntawd ntxiv degraded los ua chitosan oligosaccharides.

Lub npe Askiv: chitosan oligosaccharide / chitooligosaccharide, COS

Lub npe tshuaj: -(1→4)-2-acetylamino-2-deoxy-D-glucose

Molecular formula thiab molecular hnyav: (C8H13NO5)n

Khoom: lub teeb daj, daj, tsis muaj ntxhiab, tsis qab, soluble hauv dej

Siv chitosan ua raw khoom, degrading chitosan rau hauv me me molecules yog chitosan oligosaccharide. Nws qhov hnyav molecular yog li 3000Da, thiab qib ntawm polymerization yog 2-20. Yog li ntawd, chitosan oligosaccharide nws tus kheej yog ib qho sib tov, uas muaj monosaccharides tag nrho txoj kev mus rau chitosan decasaccharides, thiab txhua hom qab zib muaj nws cov functionality.

Chitosan oligosaccharides tuaj yeem yaj ncaj qha hauv dej, nrog rau cov dej solubility ntawm ntau tshaj 99%, thiab tib neeg nqus tus nqi ntawm 99.88%. Cov koob tshuaj thiab cov tshuaj tiv thaiv tom qab noj tau txo qis heev, thiab kev tswj hwm lub cev ncaj qha ntawm kev koom tes hauv tib neeg lub cev yog qhov tseem ceeb tshaj li chitosan, thiab nws muaj ntau txoj haujlwm zoo tshaj qhov hnyav molecular chitosan. Chitosan yuav tsum tau degraded los ntawm tib neeg lub cev biological enzymes kom tau ib co me me molecular hnyav chitosan oligosaccharides. Raws li ib txwm muaj, qhov sib piv degradation yog 1-5%, thiab qhov seem 95% ntawm polysaccharides raug tshem tawm los ntawm tib neeg txoj hnyuv. Yog li, chitosan oligosaccharides muaj txiaj ntsig zoo hauv kev ua kom lub cev tiv thaiv kab mob ntau dua li chitosan.

01. Molecular hnyav sib txawv

Chitosan oligosaccharides yog ib yam khoom tshiab uas tau txais los ntawm kev kho chitosan nrog tshwj xeeb bio-enzyme technology, nrog rau qhov hnyav molecular hauv qab 3000Da; chitosan yog ib feem ntawm deacetylation ntawm chitin, nrog rau qhov hnyav ntawm 500, 000-1 lab.

02. Solubility sib txawv

Chitosan oligosaccharides muaj qhov hnyav molecular thiab tuaj yeem ua tiav hauv dej; chitosan tsuas yog soluble hauv dilute acid kua. Kev txhim kho ntawm cov dej solubility yog qhov tseem ceeb cuam tshuam rau qee qhov kev ua haujlwm ntawm lub cev ntawm chitosan oligosaccharides. Tsuas yog thaum nws soluble hauv dej tuaj yeem nqus tau thiab siv los ntawm cov kab mob thiab qhia txog kev ua haujlwm lom neeg, yog li chitosan oligosaccharides tau yooj yim absorbed los ntawm tib neeg, tsiaj txhu thiab nroj tsuag.

03. Kev ua haujlwm txawv

Chitosan oligosaccharides nrog ib qho hnyav molecular hauv qab 2000 qhia cov haujlwm tshwj xeeb ntawm lub cev thiab kev ua haujlwm: txhim kho kev ua haujlwm ntawm macrophages; inhibiting kev loj hlob thiab metastasis ntawm cov qog hlwb; txo cov roj cholesterol thiab ntshav lipids; antibacterial, antibacterial thiab tseem ceeb moisturizing thiab hygroscopicity, thiab lwm yam.

Chitosan oligosaccharides nrog ib qho hnyav molecular hauv qab 5000 muaj peev xwm los cuam tshuam kev loj hlob thiab kev loj hlob ntawm cov kab mob, txhawb cov protein synthesis, thiab qhib cov nroj tsuag hlwb, yog li txhawb cov nroj tsuag loj hlob sai.

Ntau lub luag haujlwm ntawm chitosan oligosaccharides qhia tias nws yog lwm txoj hauv kev hauv tsev neeg oligosaccharide. Chitosan oligosaccharides yog tib yam alkaline thiab zoo them oligosaccharides pom. Qhov no feature kuj txiav txim siab tias nws tsuas yog oligosaccharide uas tuaj yeem nqus tau los ntawm cov hnyuv thiab nkag mus rau hauv cov ntshav. Nkag mus rau txhua qhov ntawm lub cev los ntawm cov ntshav ncig yog lub hauv paus rau nws ntau lwm yam kev ua haujlwm lom neeg.

Lub hauv paus rau chitosan oligosaccharides kom nqus tau los ntawm txoj hnyuv yog tias lawv tsis zom los ntawm cov enzymes digestive. Chitosan oligosaccharides yog cov polymers tsim los ntawm glucosamine txuas los ntawm -1, 4-glycosidic bonds, thiab cov enzymes digestive hauv tib neeg txoj hnyuv feem ntau ua rau -1, 4-glycosidic bonds, yog li chitosan oligosaccharides tuaj yeem tswj hwm kev ncaj ncees hauv txoj hnyuv.